Ha14 Tutorials

These tutorials assumes the steps outlined in setup have been followed first. Processing xfel data at LCLS consists of four steps:

• Averaging and other Preparatory steps
• Metrology refinement
• Indexing and integration. Optional steps:
  • Real-time progress monitoring.
  • Streaming data viewer.
  • Configuring specific spotfinder, indexing and integration parameters using phil.
• Merging
• Advanced Merging: Use cases for isomorphous replacement and de novo structure
• cctbx.prime: Merging using the prime.postrefine program.
• Resolving an Indexing Ambiguity

Additionally, cctbx.xfel utilizes phil files to manage its configuration settings.

Processing L498 thermolysin details instructions to reproduce the results published in the forthcoming cctbx.xfel paper.